The Notta Lab
We are located in the Princess Margaret Cancer Research Centre, affiliated with the Department of Medical Biophysics at the University of Toronto. Our lab is part of the PanCuRx Translational Research Initiative at the Ontario Institute for Cancer Research. The Notta Lab has made important contributions to the understanding of pancreatic cancer evolution and disease subtypes. Our lab employs genomic, cell biology and single-cell approaches to decipher new molecular targets needed to treat pancreatic cancer.
Photo Credits: University Health Network
Dr. Faiyaz Notta, senior and Allan Slaight Scientist at PM, received $5.3 million to lead the ELDER Study, a collaboration between Canadian and Japanese researchers investigating how aging biology contributes to early‑onset colorectal and pancreatic cancers — diseases that are increasingly diagnosed in younger adults.
"By studying the microbiome, genetic mutations and age‑related epigenetic changes, we aim to understand why the rates of these cancers are rising and how to detect them sooner," said Dr. Notta.
February 26, 2026
University of Waterloo 2023 Employer Impact In Research Award
“Waterloo co-op students working at the Notta lab at UHN play a critical role in researching pancreatic cancer. As research laboratory assistants, students study and analyze tumour cells for a research repository” (University of Waterloo, 2023).
Read more here: Waterloo co-op students are at the forefront of pancreatic cancer research at UHN
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